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N-Fluorobenzenesulfonimide is mainly used as fluorinating agent, it can be used for the monofluorination of electron rich aromatic compounds, enolsilane, enollithium salt and so on.
N-fluorobenzenesulfonimide
NFSi for short
Formula: C12H10FNO4S2
Molecular Weight: 315.3
CAS No.: 133745-75-2
N-fluorobenzenesulfonimide is a stable and mild fluorination reagent, which is used for the monofluorination of electron-rich aromatic compounds, silyl enol ether, lithium enolates, etc.
NFSi can perform electrophilic fluorination on aldehydes, ketones, esters and other substrates with high enantioselectivity.
NFSi can perform electrophilic fluorination reactions on aldehydes, ketones, esters and other substrates with high enantioselectivity. It can be used as a fluorine reagent to add double bonds.
As a fluorine reagent, it can fluoridate aromatic compounds. Palladium-catalyzed enantioselective fluorination of tert-butoxy-carbonyl lactones and lactam compounds; It is used for electrophilic difluorination of dihalopyridine compounds under the action of butyl lithium and for direct conversion of alcohols under the action of triphenylphosphine to diphenyl sulfonimide compounds.
